Light, light, light. Adequate lighting will result in sharper images and also result in better focus as your camera aperture closes automatically. This results in a better depth of field. Avoid hard shadows by bouncing the light off the ceiling. Look for lights at your local photographic or hardware store which offer 500w - 800w. Using 2 lights properly placed will soften annoying shadows.
Use a tripod. Excessive camera movement will strain the compression codec used on internet video resulting in blocky images. When using a tripod only the areas that have movement will be processed from one frame to the next. With less processing required your images will be sharper with no extra effort on your part.
Avoid the temptation to add music. Natural sound is far more real and allows the viewer to better 'feel the moment'. Music also adds additional strain to the compression codecs mentioned above.
Most of all - have fun!
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